Pharmaceutical Technology: Controlled Drug Release - Volume 2

Extends the concepts of Volume 1 to include drug properties, design and optimization, coating, and the effect of food and pharmacokinetics. This volume also reflects the growing interest in biodegradable polymers in oral and topical formulations and the use of sterile implants.

The field of pharmaceutical technology is constantly evolving, and controlled drug release is an important aspect of this field. The second volume of the Handbook of Pharmaceutical Technology: Controlled Drug Release, edited by Professor M.H. Rubinstein of the School of Health Sciences at Liverpool Polytechnic, provides a comprehensive overview of the latest developments in this area.

The controlled release of drugs is important because it allows for the slow and steady delivery of medications to the body. This can be especially useful in cases where medication needs to be taken over a long period of time, such as for chronic conditions like diabetes or hypertension. Controlled drug release can also be used to improve the efficacy of certain drugs, by ensuring that they are delivered to the right part of the body at the right time.

The Handbook of Pharmaceutical Technology: Controlled Drug Release - Volume 2 is a valuable resource for researchers, scientists, and students in the field of pharmaceutical technology. The book is divided into several chapters, each of which covers a different aspect of controlled drug release.

The book's first part concentrates on matrix systems, the central part with multi-particle formulations, and the closing section with an examination of opportunities with biodegradable polymers. Although the oral route remains the primary application form, the authors also include information on topical ophthalmics and implants. Based on two recent pharmaceutical technology conferences, one in Monte Carlo in 1989 and the other in Holland in 1990, this book provides a foundation on which the reader can increase his knowledge of controlled drug release.

The first chapter provides an overview of the principles of controlled drug release. This includes an explanation of the different types of drug delivery systems, such as oral, transdermal, and inhalation systems. The chapter also discusses the various factors that can affect drug release, such as the physicochemical properties of the drug, the design of the drug delivery system, and the biological environment in which the drug is released.

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The second chapter focuses on the design and development of drug delivery systems. This includes an overview of the different types of drug delivery systems that are currently available, as well as the factors that need to be considered when designing a new drug delivery system. The chapter also discusses the various materials that can be used to create drug delivery systems, such as polymers, lipids, and metals.

The third chapter covers the different types of drug delivery systems that are currently available. This includes an overview of the different types of oral drug delivery systems, such as immediate release, delayed release, and sustained release systems. The chapter also discusses transdermal drug delivery systems, inhalation drug delivery systems, and implantable drug delivery systems.

The fourth chapter focuses on the challenges and opportunities in the field of controlled drug release. This includes an overview of the regulatory environment that surrounds the development of drug delivery systems, as well as the ethical considerations that need to be taken into account when developing new drugs. The chapter also discusses the various technological advances that are currently being made in the field of controlled drug release, and the potential implications of these advances for the future of medicine.

The fifth chapter provides a case study of a successful controlled drug release system. This includes an overview of the development and commercialization of the Exelon Patch, a transdermal drug delivery system used to treat Alzheimer's disease. The case study provides insights into the challenges and opportunities that arise when developing a new drug delivery system, and the various factors that need to be considered in order to achieve success.

Overall, the Handbook of Pharmaceutical Technology: Controlled Drug Release - Volume 2 is an essential resource for anyone working in the field of pharmaceutical technology. The book provides a comprehensive overview of the latest developments in controlled drug release and is sure to be of interest to researchers, scientists, and students alike

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