SOP for Cleaning Procedure of Karl Fischer Apparatus

OBJECTIVE

To lay down the procedure for cleaning the KF Apparatus.

SCOPE

This SOP shall apply to the KF Apparatus installed in the Quality Control Laboratory.

RESPONSIBILITY

Execution: Chemist and above-QC department

PROCEDURE

Frequency: After each use

• After completion of the analysis, open the titration flask pour the KF reagent into the KF waste bottle, and wash the vessel with of methanol.
• Clean the electrode with the help of tissue paper.

• Clean the outer surface of the instrument with Isopropyl alcohol (when required) and dry it with tissue paper.
• As and when required, replace the ‘self-indicating’ coarse silica
• If the color of the silica gel changes from blue to pink, regenerate the silica gel by keeping it in the oven for some time till it gets blue color again.
• After cleaning the KF apparatus, record the cleaning details in the instrument log card as per the current version of the SOP.

ABBREVIATION

SOP: Standard Operating Procedure

Q.C: Quality control

KF: Karl Fischer

ANNEXURE

Nil

REVISION HISTORY

Nil

ALSO READ: SOP for Operation and Calibration of Karl Fischer Apparatus