SOP for Cleaning Procedure of Empty PVC Bottles

OBJECTIVE

To lay down a procedure for cleaning of empty PVC Bottles.

SCOPE

This procedure applies for the Beta-Lactam production department in the Pharmaceutical Manufacturing Facilities of XYZ Limited, Formulation division. This procedure covers the cleaning of empty PVC bottles.

RESPONSIBILITY

The beta-lactam dry syrup filling operator is responsible for the implementation of the process.

The Beta-Lactam In-Charge is responsible for the execution and compliance of the procedure.

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PROCEDURE

• Carry the bottles to the bottles inspection area, unload and inspect them and reject damaged bottles before sending them for cleaning.
• Turn on the compressor and switch ON the blower and check that dry air is blown.
• Hold the bottles in an inverted, upside-down position on the blower neck and pass dry compressed air in the bottles.
• Switch OFF the blower and compressor.

• Visually inspect the bottles after blowing and reject any damaged or uncleaned bottles.
• Check the bulb and remove water collected from the compressed air with line.
• Take these cleaned bottles to the filling area, and use them for filling of dry syrup.
• The balance of the remaining bottles should be returned to the store.
• Check the pressure and compressor valves for leakage daily.

ABBREVIATION

Q.A: Quality Assurance

BL: Beta-Lactam

SCP: Standard Cleaning Procedure

No. : Number

P.D: Production

PVC : Polyvinyl chloride

ANNEXURE

Nil

REVISION HISTORY

Nil

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